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BMCBI
2007
123views more  BMCBI 2007»
13 years 8 months ago
BIRCH: A user-oriented, locally-customizable, bioinformatics system
Background: Molecular biologists need sophisticated analytical tools which often demand extensive computational resources. While finding, installing, and using these tools can be ...
Brian Fristensky
BMCBI
2007
111views more  BMCBI 2007»
13 years 8 months ago
MotifCombinator: a web-based tool to search for combinations of cis-regulatory motifs
Background: A combination of multiple types of transcription factors and cis-regulatory elements is often required for gene expression in eukaryotes, and the combinatorial regulat...
Mamoru Kato, Tatsuhiko Tsunoda
BMCBI
2007
180views more  BMCBI 2007»
13 years 8 months ago
Using expression arrays for copy number detection: an example from E. coli
Background: The sequencing of many genomes and tiling arrays consisting of millions of DNA segments spanning entire genomes have made high-resolution copy number analysis possible...
Dmitriy Skvortsov, Diana Abdueva, Michael E. Stitz...
BMCBI
2007
147views more  BMCBI 2007»
13 years 8 months ago
Bias in random forest variable importance measures: Illustrations, sources and a solution
Variable importance measures for random forests have been receiving increased attention as a means of variable selection in many classification tasks in bioinformatics and relate...
Carolin Strobl, Anne-Laure Boulesteix, Achim Zeile...
EOR
2006
135views more  EOR 2006»
13 years 8 months ago
Principles of scatter search
Scatter search is an evolutionary method that has been successfully applied to hard optimization problems. The fundamental concepts and principles of the method were first propose...
Rafael Martí, Manuel Laguna, Fred Glover