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» A polyhedral approach to sequence alignment problems
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RECOMB
2001
Springer
14 years 7 months ago
A new approach to sequence comparison: normalized sequence alignment
The Smith-Waterman algorithm for local sequence alignment is one of the most important techniques in computational molecular biology. This ingenious dynamic programming approach w...
Abdullah N. Arslan, Ömer Egecioglu, Pavel A. ...
RECOMB
2009
Springer
14 years 8 months ago
Simultaneous Alignment and Folding of Protein Sequences
Abstract. Accurate comparative analysis tools for low-homology proteins remains a difficult challenge in computational biology, especially sequence alignment and consensus folding ...
Bonnie Berger, Charles W. O'Donnell, Jér&oc...
RECOMB
2012
Springer
11 years 9 months ago
Estimating the Accuracy of Multiple Alignments and its Use in Parameter Advising
We develop a novel and general approach to estimating the accuracy of protein multiple sequence alignments without knowledge of a reference alignment, and use our approach to addre...
Dan F. DeBlasio, Travis J. Wheeler, John D. Kececi...
BIB
2006
141views more  BIB 2006»
13 years 7 months ago
Statistical significance in biological sequence analysis
One of the major goals of computational sequence analysis is to find sequence similarities, which could serve as evidence of structural and functional conservation, as well as of ...
Alexander Yu. Mitrophanov, Mark Borodovsky
CC
2008
Springer
193views System Software» more  CC 2008»
13 years 9 months ago
Automatic Transformations for Communication-Minimized Parallelization and Locality Optimization in the Polyhedral Model
The polyhedral model provides powerful abstractions to optimize loop nests with regular accesses. Affine transformations in this model capture a complex sequence of execution-reord...
Uday Bondhugula, Muthu Manikandan Baskaran, Sriram...