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BMCBI
2010
136views more  BMCBI 2010»
13 years 7 months ago
Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfa
Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...
BMCBI
2006
137views more  BMCBI 2006»
13 years 7 months ago
Bounded search for de novo identification of degenerate cis-regulatory elements
Background: The identification of statistically overrepresented sequences in the upstream regions of coregulated genes should theoretically permit the identification of potential ...
Jonathan M. Carlson, Arijit Chakravarty, Radhika S...
BMCBI
2007
115views more  BMCBI 2007»
13 years 7 months ago
Recognizing protein-protein interfaces with empirical potentials and reduced amino acid alphabets
Background: In structural genomics, an important goal is the detection and classification of protein–protein interactions, given the structures of the interacting partners. We h...
Guillaume Launay, Raul Mendez, Shoshana J. Wodak, ...
WWW
2008
ACM
13 years 7 months ago
Divide, Compress and Conquer: Querying XML via Partitioned Path-Based Compressed Data Blocks
We propose a novel Partition Path-Based (PPB) grouping strategy to store compressed XML data in a stream of blocks. In addition, we employ a minimal indexing scheme called Block S...
Wilfred Ng, Ho Lam Lau, Aoying Zhou
TIP
2002
131views more  TIP 2002»
13 years 7 months ago
Optimal edge-based shape detection
Abstract--We propose an approach to accurately detecting twodimensional (2-D) shapes. The cross section of the shape boundary is modeled as a step function. We first derive a one-d...
Hankyu Moon, Rama Chellappa, Azriel Rosenfeld