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BMCBI
2010
13 years 7 months ago
2010
Background: Codon bias is believed to play an important role in the control of gene expression. In Escherichia coli, some rare codons, which can limit the expression level of exog...
BMCBI
2010
13 years 7 months ago
2010
Background: This paper introduces the notion of optimizing different norms in the dual problem of support vector machines with multiple kernels. The selection of norms yields diff...
BMCBI
2010
13 years 7 months ago
2010
Background: Gene silencing using exogenous small interfering RNAs (siRNAs) is now a widespread molecular tool for gene functional study and new-drug target identification. The key...
BMCBI
2010
13 years 7 months ago
2010
Background: Human genome contains millions of common single nucleotide polymorphisms (SNPs) and these SNPs play an important role in understanding the association between genetic ...
BMCBI
2010
13 years 7 months ago
2010
Background: High-throughput DNA methylation arrays are likely to accelerate the pace of methylation biomarker discovery for a wide variety of diseases. A potential problem with a ...