Background: The small sample sizes often used for microarray experiments result in poor estimates of variance if each gene is considered independently. Yet accurately estimating v...
Maureen A. Sartor, Craig R. Tomlinson, Scott C. We...
Background: A major goal of cancer research is to identify discrete biomarkers that specifically characterize a given malignancy. These markers are useful in diagnosis, may identi...
Virginie M. Aris, Michael J. Cody, Jeff Cheng, Jam...
Background: It is an important pre-processing step to accurately estimate missing values in microarray data, because complete datasets are required in numerous expression profile ...
Background: High-density short oligonucleotide microarrays are a primary research tool for assessing global gene expression. Background noise on microarrays comprises a significan...
Background: Microarrays are widely used for the study of gene expression; however deciding on whether observed differences in expression are significant remains a challenge. Resul...