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» A scalable algorithm for clustering protein sequences
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SDM
2007
SIAM
117views Data Mining» more  SDM 2007»
13 years 9 months ago
Discriminating Subsequence Discovery for Sequence Clustering
In this paper, we explore the discriminating subsequencebased clustering problem. First, several effective optimization techniques are proposed to accelerate the sequence mining p...
Jianyong Wang, Yuzhou Zhang, Lizhu Zhou, George Ka...
BIBE
2007
IEEE
128views Bioinformatics» more  BIBE 2007»
14 years 2 months ago
QOMA2: Optimizing the alignment of many sequences
Abstract—We consider the problem of aligning multiple protein sequences with the goal of maximizing the SP (Sum-of-Pairs) score, when the number of sequences is large. The QOMA (...
Xu Zhang, Tamer Kahveci
BMCBI
2011
12 years 11 months ago
Protein alignment algorithms with an efficient backtracking routine on multiple GPUs
Background: Pairwise sequence alignment methods are widely used in biological research. The increasing number of sequences is perceived as one of the upcoming challenges for seque...
Jacek Blazewicz, Wojciech Frohmberg, Michal Kierzy...
ALMOB
2006
109views more  ALMOB 2006»
13 years 8 months ago
A novel functional module detection algorithm for protein-protein interaction networks
Background: The sparse connectivity of protein-protein interaction data sets makes identification of functional modules challenging. The purpose of this study is to critically eva...
Woochang Hwang, Young-Rae Cho, Aidong Zhang, Mural...
BMCBI
2006
144views more  BMCBI 2006»
13 years 8 months ago
Development and implementation of an algorithm for detection of protein complexes in large interaction networks
Background: After complete sequencing of a number of genomes the focus has now turned to proteomics. Advanced proteomics technologies such as two-hybrid assay, mass spectrometry e...
Md. Altaf-Ul-Amin, Yoko Shinbo, Kenji Mihara, Ken ...