Background: As numerous diseases involve errors in signal transduction, modern therapeutics often target proteins involved in cellular signaling. Interpretation of the activity of...
Background: With the explosion in data generated using microarray technology by different investigators working on similar experiments, it is of interest to combine results across...
Hyungwon Choi, Ronglai Shen, Arul M. Chinnaiyan, D...
Background: Statistical methods for ranking differentially expressed genes (DEGs) from gene expression data should be evaluated with regard to high sensitivity, specificity, and r...
Biological research is currently undergoing a revolution. With the advent of microarray technology the behavior of thousands of genes can be measured simultaneously. This capabilit...
Herman Midelfart, Henryk Jan Komorowski, Kristin N...
Background: The goal of most microarray studies is either the identification of genes that are most differentially expressed or the creation of a good classification rule. The dis...