93 search results - page 1 / 19 » A statistical approach to finding overlooked genetic associa... |
BMCBI
2010
13 years 7 months ago
2010
Background: Complexity and noise in expression quantitative trait loci (eQTL) studies make it difficult to distinguish potential regulatory relationships among the many interactio...
BMCBI
2005
13 years 7 months ago
2005
Background: Synthetic lethality experiments identify pairs of genes with complementary function. More direct functional associations (for example greater probability of membership...
BMCBI
2011
12 years 11 months ago
2011
Background: Discovering the genetic basis of common genetic diseases in the human genome represents a public health issue. However, the dimensionality of the genetic data (up to 1...
BMCBI
2006
13 years 7 months ago
2006
Background: We present a general approach to perform association analyses in pedigrees of arbitrary size and structure, which also allows for a mixture of pedigree members and ind...
BMCBI
2008
13 years 7 months ago
2008
Background: Researchers wishing to conduct genetic association analysis involving single nucleotide polymorphisms (SNPs) or haplotypes are often confronted with the lack of user-f...