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BIOINFORMATICS
2012
12 years 5 days ago
Epigenetic priors for identifying active transcription factor binding sites
Motivation Accurate knowledge of the genome-wide binding of transcription factors in a particular cell type or under a particular condition is necessary for understanding transcri...
Gabriel Cuellar-Partida, Fabian A. Buske, Robert C...
BMCBI
2010
233views more  BMCBI 2010»
13 years 10 months ago
Odefy -- From discrete to continuous models
Background: Phenomenological information about regulatory interactions is frequently available and can be readily converted to Boolean models. Fully quantitative models, on the ot...
Jan Krumsiek, Sebastian Pölsterl, Dominik M. ...
BMCBI
2007
114views more  BMCBI 2007»
13 years 10 months ago
Mining and state-space modeling and verification of sub-networks from large-scale biomolecular networks
Background: Biomolecular networks dynamically respond to stimuli and implement cellular function. Understanding these dynamic changes is the key challenge for cell biologists. As ...
Xiaohua Hu, Fang-Xiang Wu
RE
2001
Springer
14 years 2 months ago
Virtual Environment Modeling for Requirements Validation of High Consequence Systems
An essential type of “evidence”of the correctness of the requirements formalization process can be provided by human-based calculation. Human calculation can be significantly ...
Victor L. Winter, Dejan Desovski, Bojan Cukic
ESWA
2006
103views more  ESWA 2006»
13 years 9 months ago
Model gene network by semi-fixed Bayesian network
Gene networks describe functional pathways in a given cell or tissue, representing processes such as metabolism, gene expression regulation, and protein or RNA transport. Thus, le...
Tie-Fei Liu, Wing-Kin Sung, Ankush Mittal