Motivation Accurate knowledge of the genome-wide binding of transcription factors in a particular cell type or under a particular condition is necessary for understanding transcri...
Gabriel Cuellar-Partida, Fabian A. Buske, Robert C...
Background: Phenomenological information about regulatory interactions is frequently available and can be readily converted to Boolean models. Fully quantitative models, on the ot...
Background: Biomolecular networks dynamically respond to stimuli and implement cellular function. Understanding these dynamic changes is the key challenge for cell biologists. As ...
An essential type of “evidence”of the correctness of the requirements formalization process can be provided by human-based calculation. Human calculation can be significantly ...
Gene networks describe functional pathways in a given cell or tissue, representing processes such as metabolism, gene expression regulation, and protein or RNA transport. Thus, le...