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BIOCOMP
2006
13 years 9 months ago
An Approach to Selecting Putative RNA Motifs Using MDL Principle
The history of molecular biology is punctuated by a series of discoveries demonstrating the surprising breadth of biological roles of ribonucleic acid (RNA). An ensemble of evoluti...
Mohammad Anwar, Marcel Turcotte
BMCBI
2010
136views more  BMCBI 2010»
13 years 7 months ago
Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfa
Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...
BIOINFORMATICS
2011
12 years 11 months ago
A method for probing the mutational landscape of amyloid structure
Motivation: Proteins of all kinds can self-assemble into highly ordered β-sheet aggregates known as amyloid fibrils, important both biologically and clinically. However, the spe...
Charles W. O'Donnell, Jérôme Waldisp&...
ICDM
2008
IEEE
182views Data Mining» more  ICDM 2008»
14 years 2 months ago
Multiple-Instance Regression with Structured Data
We present a multiple-instance regression algorithm that models internal bag structure to identify the items most relevant to the bag labels. Multiple-instance regression (MIR) op...
Kiri L. Wagstaff, Terran Lane, Alex Roper
IM
2007
13 years 9 months ago
Estimating End-to-End Performance by Collaborative Prediction with Active Sampling
— Accurately estimating end-to-end performance in distributed systems is essential both for monitoring compliance with service-level agreements (SLAs) and for performance optimiz...
Irina Rish, Gerald Tesauro