The history of molecular biology is punctuated by a series of discoveries demonstrating the surprising breadth of biological roles of ribonucleic acid (RNA). An ensemble of evoluti...
Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...
Motivation: Proteins of all kinds can self-assemble into highly ordered β-sheet aggregates known as amyloid fibrils, important both biologically and clinically. However, the spe...
We present a multiple-instance regression algorithm that models internal bag structure to identify the items most relevant to the bag labels. Multiple-instance regression (MIR) op...
— Accurately estimating end-to-end performance in distributed systems is essential both for monitoring compliance with service-level agreements (SLAs) and for performance optimiz...