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BMCBI
2006
160views more  BMCBI 2006»
15 years 4 months ago
Gene prediction in eukaryotes with a generalized hidden Markov model that uses hints from external sources
Background: In order to improve gene prediction, extrinsic evidence on the gene structure can be collected from various sources of information such as genome-genome comparisons an...
Mario Stanke, Oliver Schöffmann, Burkhard Mor...
176
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BMCBI
2006
156views more  BMCBI 2006»
15 years 4 months ago
Score-based prediction of genomic islands in prokaryotic genomes using hidden Markov models
Background: Horizontal gene transfer (HGT) is considered a strong evolutionary force shaping the content of microbial genomes in a substantial manner. It is the difference in spee...
Stephan Waack, Oliver Keller, Roman Asper, Thomas ...
BMCBI
2006
101views more  BMCBI 2006»
15 years 4 months ago
How repetitive are genomes?
Background: Genome sequences vary strongly in their repetitiveness and the causes for this are still debated. Here we propose a novel measure of genome repetitiveness, the index o...
Bernhard Haubold, Thomas Wiehe
IANDC
2008
92views more  IANDC 2008»
15 years 4 months ago
Tree exploration with advice
We study the amount of knowledge about the network that is required in order to efficiently solve a task concerning this network. The impact of available information on the effici...
Pierre Fraigniaud, David Ilcinkas, Andrzej Pelc
156
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BMCBI
2007
164views more  BMCBI 2007»
15 years 4 months ago
SEARCHPATTOOL: a new method for mining the most specific frequent patterns for binding sites with application to prokaryotic DNA
Background: Computational methods to predict transcription factor binding sites (TFBS) based on exhaustive algorithms are guaranteed to find the best patterns but are often limite...
Fathi Elloumi, Martha Nason