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BMCBI
2010
117views more  BMCBI 2010»
13 years 7 months ago
Identification of NAD interacting residues in proteins
Background: Small molecular cofactors or ligands play a crucial role in the proper functioning of cells. Accurate annotation of their target proteins and binding sites is required...
Hifzur Rahman Ansari, Gajendra P. S. Raghava
ISMB
2000
13 years 9 months ago
Pattern Recognition of Genomic Features with Microarrays: Site Typing of Mycobacterium Tuberculosis Strains
Mycobacterium tuberculosis (M. tb.) strains differ in the number and locations of a transposon-like insertion sequence known as IS6110. Accurate detection of this sequence can be ...
Soumya Raychaudhuri, Joshua M. Stuart, Xuemin Liu,...
BMCBI
2008
102views more  BMCBI 2008»
13 years 7 months ago
Combining sequence-based prediction methods and circular dichroism and infrared spectroscopic data to improve protein secondary
Background: A number of sequence-based methods exist for protein secondary structure prediction. Protein secondary structures can also be determined experimentally from circular d...
Jonathan G. Lees, Robert W. Janes
GECCO
2006
Springer
124views Optimization» more  GECCO 2006»
13 years 11 months ago
Genetic programming for human oral bioavailability of drugs
Automatically assessing the value of bioavailability from the chemical structure of a molecule is a very important issue in biomedicine and pharmacology. In this paper, we present...
Francesco Archetti, Stefano Lanzeni, Enza Messina,...
BMCBI
2007
141views more  BMCBI 2007»
13 years 7 months ago
Artificial neural network models for prediction of intestinal permeability of oligopeptides
Background: Oral delivery is a highly desirable property for candidate drugs under development. Computational modeling could provide a quick and inexpensive way to assess the inte...
Eunkyoung Jung, Junhyoung Kim, Minkyoung Kim, Dong...