Background: Currently, clustering with some form of correlation coefficient as the gene similarity metric has become a popular method for profiling genomic data. The Pearson corre...
Jianchao Yao, Chunqi Chang, Mari L. Salmi, Yeung S...
Background: The Thymidine kinase (Tk) mutants generated from the widely used L5178Y mouse lymphoma assay fall into two categories, small colony and large colony. Cells from the la...
Tao Han, Jianyong Wang, Weida Tong, Martha M. Moor...
The Gene Ontology (GO) is an important knowledge resource for biologists and bioinformaticians. This paper explores the integration of similarity information derived from GO into ...
Haiying Wang, Francisco Azuaje, Olivier Bodenreide...
Background: Microarray co-expression signatures are an important tool for studying gene function and relations between genes. In addition to genuine biological co-expression, corr...
Background: Retinal photoreceptors are highly specialised cells, which detect light and are central to mammalian vision. Many retinal diseases occur as a result of inherited dysfu...
Haiying Wang, Huiru Zheng, David Simpson, Francisc...