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BMCBI
2007
13 years 7 months ago
2007
Background: Remote homology detection is a challenging problem in Bioinformatics. Arguably, profile Hidden Markov Models (pHMMs) are one of the most successful approaches in addre...
ACMMSP
2004
ACM
14 years 27 days ago
2004
ACM
As superscalar processors become increasingly wide, it is inevitable that the large set of instructions to be fetched every cycle will span multiple noncontiguous basic blocks. Th...
BMCBI
2007
13 years 7 months ago
2007
Background: The presence of gaps in an alignment of nucleotide or protein sequences is often an inconvenience for bioinformatical studies. In phylogenetic and other analyses, for ...
BMCBI
2006
2006
On single and multiple models of protein families for the detection of remote sequence relationships
13 years 7 months ago
Background: The detection of relationships between a protein sequence of unknown function and a sequence whose function has been characterised enables the transfer of functional a...
BMCBI
2005
13 years 7 months ago
2005
Background: Profile hidden Markov model (HMM) techniques are among the most powerful methods for protein homology detection. Yet, the critical features for successful modelling ar...