89 search results - page 15 / 18 » Ab initio Prediction of Transcription Factor Binding Sites |
BMCBI
2006
13 years 7 months ago
2006
Background: Identifying functional elements, such as transcriptional factor binding sites, is a fundamental step in reconstructing gene regulatory networks and remains a challengi...
JCB
2008
13 years 7 months ago
2008
We present BayesMD, a Bayesian Motif Discovery model with several new features. Three different types of biological a priori knowledge are built into the framework in a modular fa...
BMCBI
2007
13 years 7 months ago
2007
Background: This work explores the quantitative characteristics of the local transcriptional regulatory network based on the availability of time dependent gene expression data se...
BIOINFORMATICS
2006
13 years 7 months ago
2006
Motivation: Over 50% of human genes contain CpG islands in their 5'-regions. Methylation patterns of CpG islands are involved in tissue-specific gene expression and regulatio...
BMCBI
2006
13 years 7 months ago
2006
Background: We have recently introduced a predictive framework for studying gene transcriptional regulation in simpler organisms using a novel supervised learning algorithm called...