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ICCS
2005
Springer
14 years 1 months ago
Modelling Dynamics of Genetic Networks as a Multiscale Process
A key phenomenon in the dynamics of genetic networks is the cell cycle. In the study of this phenomenon, an important task is to understand how many processes, acting on different...
Xilin Wei, Roderick V. N. Melnik, Gabriel Moreno-H...
HYBRID
2007
Springer
14 years 2 months ago
Switch Detection in Genetic Regulatory Networks
Abstract. This paper considers piecewise affine models of genetic regulatory networks and focuses on the problem of detecting switches among different modes of operation in gene e...
Riccardo Porreca, Giancarlo Ferrari-Trecate, Danie...
BIB
2008
109views more  BIB 2008»
13 years 8 months ago
Computational intelligence approaches for pattern discovery in biological systems
Biology, chemistry and medicine are faced by tremendous challenges caused by an overwhelming amount of data and the need for rapid interpretation. Computational intelligence (CI) ...
Gary B. Fogel
GECCO
2006
Springer
220views Optimization» more  GECCO 2006»
14 years 2 days ago
Comparing evolutionary algorithms on the problem of network inference
In this paper, we address the problem of finding gene regulatory networks from experimental DNA microarray data. We focus on the evaluation of the performance of different evoluti...
Christian Spieth, Rene Worzischek, Felix Streicher...
BMCBI
2007
122views more  BMCBI 2007»
13 years 8 months ago
Dissecting complex transcriptional responses using pathway-level scores based on prior information
Background: The genomewide pattern of changes in mRNA expression measured using DNA microarrays is typically a complex superposition of the response of multiple regulatory pathway...
Harmen J. Bussemaker, Lucas D. Ward, André ...