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CIKM
2006
Springer
13 years 11 months ago
Evaluation by comparing result sets in context
Familiar evaluation methodologies for information retrieval (IR) are not well suited to the task of comparing systems in many real settings. These systems and evaluation methods m...
Paul Thomas, David Hawking
BMCBI
2010
124views more  BMCBI 2010»
13 years 7 months ago
Estimation and efficient computation of the true probability of recurrence of short linear protein sequence motifs in unrelated
Background: Large datasets of protein interactions provide a rich resource for the discovery of Short Linear Motifs (SLiMs) that recur in unrelated proteins. However, existing met...
Norman E. Davey, Richard J. Edwards, Denis C. Shie...
BMCBI
2008
144views more  BMCBI 2008»
13 years 7 months ago
Local conservation scores without a priori assumptions on neutral substitution rates
Background: Comparative genomics aims to detect signals of evolutionary conservation as an indicator of functional constraint. Surprisingly, results of the ENCODE project revealed...
Janis Dingel, Pavol Hanus, Niccolò Leonardi...
BMCBI
2007
106views more  BMCBI 2007»
13 years 7 months ago
Modeling SAGE tag formation and its effects on data interpretation within a Bayesian framework
Background: Serial Analysis of Gene Expression (SAGE) is a high-throughput method for inferring mRNA expression levels from the experimentally generated sequence based tags. Stand...
Michael A. Gilchrist, Hong Qin, Russell L. Zaretzk...
ISCI
2008
165views more  ISCI 2008»
13 years 7 months ago
Support vector regression from simulation data and few experimental samples
This paper considers nonlinear modeling based on a limited amount of experimental data and a simulator built from prior knowledge. The problem of how to best incorporate the data ...
Gérard Bloch, Fabien Lauer, Guillaume Colin...