Familiar evaluation methodologies for information retrieval (IR) are not well suited to the task of comparing systems in many real settings. These systems and evaluation methods m...
Background: Large datasets of protein interactions provide a rich resource for the discovery of Short Linear Motifs (SLiMs) that recur in unrelated proteins. However, existing met...
Norman E. Davey, Richard J. Edwards, Denis C. Shie...
Background: Comparative genomics aims to detect signals of evolutionary conservation as an indicator of functional constraint. Surprisingly, results of the ENCODE project revealed...
Background: Serial Analysis of Gene Expression (SAGE) is a high-throughput method for inferring mRNA expression levels from the experimentally generated sequence based tags. Stand...
Michael A. Gilchrist, Hong Qin, Russell L. Zaretzk...
This paper considers nonlinear modeling based on a limited amount of experimental data and a simulator built from prior knowledge. The problem of how to best incorporate the data ...