Background: The inference of homology from statistically significant sequence similarity is a central issue in sequence alignments. So far the statistical distribution function un...
Background: Sequence alignment is a common tool in bioinformatics and comparative genomics. It is generally assumed that multiple sequence alignment yields better results than pai...
Background: Procedures for genetic analyses based on oligonucleotide probes are powerful tools that can allow highly parallel investigations of genetic material. Such procedures r...
Background: Predicting the subcellular localization of proteins is important for determining the function of proteins. Previous works focused on predicting protein localization in...
Background: The identification of local similarities between two protein structures can provide clues of a common function. Many different methods exist for searching for similar ...