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» Active Clustering of Biological Sequences
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BMCBI
2008
167views more  BMCBI 2008»
13 years 7 months ago
Expression profiles of switch-like genes accurately classify tissue and infectious disease phenotypes in model-based classificat
Background: Large-scale compilation of gene expression microarray datasets across diverse biological phenotypes provided a means of gathering a priori knowledge in the form of ide...
Michael Gormley, Aydin Tozeren
BMCBI
2006
98views more  BMCBI 2006»
13 years 7 months ago
Quantitative comparison of EST libraries requires compensation for systematic biases in cDNA generation
Background: Publicly accessible EST libraries contain valuable information that can be utilized for studies of tissue-specific gene expression and processing of individual genes. ...
Donglin Liu, Joel H. Graber
BMCBI
2007
147views more  BMCBI 2007»
13 years 7 months ago
Statistical analysis and significance testing of serial analysis of gene expression data using a Poisson mixture model
Background: Serial analysis of gene expression (SAGE) is used to obtain quantitative snapshots of the transcriptome. These profiles are count-based and are assumed to follow a Bin...
Scott D. Zuyderduyn
BMCBI
2006
144views more  BMCBI 2006»
13 years 7 months ago
Development and implementation of an algorithm for detection of protein complexes in large interaction networks
Background: After complete sequencing of a number of genomes the focus has now turned to proteomics. Advanced proteomics technologies such as two-hybrid assay, mass spectrometry e...
Md. Altaf-Ul-Amin, Yoko Shinbo, Kenji Mihara, Ken ...
RECOMB
2000
Springer
13 years 11 months ago
Contig selection in physical mapping
In physical mapping, one orders a set of genetic landmarks or a library of cloned fragments of DNA according to their position in the genome. Our approach to physical mapping divi...
Steffen Heber, Jens Stoye, Jörg D. Hoheisel, ...