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BMCBI
2006
88views more  BMCBI 2006»
13 years 11 months ago
Protein kinases associated with the yeast phosphoproteome
Background: Protein phosphorylation is an extremely important mechanism of cellular regulation. A large-scale study of phosphoproteins in a whole-cell lysate of Saccharomyces cere...
Ross I. Brinkworth, Alan L. Munn, Bostjan Kobe
BMCBI
2006
94views more  BMCBI 2006»
13 years 11 months ago
Fly-DPI: database of protein interactomes for D. melanogaster in the approach of systems biology
Background: Proteins control and mediate many biological activities of cells by interacting with other protein partners. This work presents a statistical model to predict protein ...
Chung-Yen Lin, Shu-Hwa Chen, Chi-Shiang Cho, Chia-...
BMCBI
2006
130views more  BMCBI 2006»
13 years 11 months ago
Docking protein domains in contact space
Background: Many biological processes involve the physical interaction between protein domains. Understanding these functional associations requires knowledge of the molecular str...
Stefano Lise, Alice Walker-Taylor, David T. Jones
BMCBI
2006
88views more  BMCBI 2006»
13 years 11 months ago
RiboSubstrates: a web application addressing the cleavage specificities of ribozymes in designated genomes
Background: RNA-dependent gene silencing is becoming a routine tool used in laboratories worldwide. One of the important remaining hurdles in the selection of the target sequence,...
Jean-François Lucier, Lucien Junior Bergero...
BMCBI
2006
128views more  BMCBI 2006»
13 years 11 months ago
Model-driven user interfaces for bioinformatics data resources: regenerating the wheel as an alternative to reinventing it
Background: The proliferation of data repositories in bioinformatics has resulted in the development of numerous interfaces that allow scientists to browse, search and analyse the...
Kevin L. Garwood, Christopher Garwood, Cornelia He...