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BMCBI
2008
118views more  BMCBI 2008»
13 years 8 months ago
Drug interaction prediction using ontology-driven hypothetical assertion framework for pathway generation followed by numerical
Background: In accordance with the increasing amount of information concerning individual differences in drug response and molecular interaction, the role of in silico prediction ...
Takeshi Arikuma, Sumi Yoshikawa, Ryuzo Azuma, Kent...
BMCBI
2006
111views more  BMCBI 2006»
13 years 7 months ago
Development of an unbiased statistical method for the analysis of unigenic evolution
Background: Unigenic evolution is a powerful genetic strategy involving random mutagenesis of a single gene product to delineate functionally important domains of a protein. This ...
Colleen D. Behrsin, Chris J. Brandl, David W. Litc...
BMCBI
2006
205views more  BMCBI 2006»
13 years 7 months ago
Application of Petri net based analysis techniques to signal transduction pathways
Background: Signal transduction pathways are usually modelled using classical quantitative methods, which are based on ordinary differential equations (ODEs). However, some diffic...
Andrea Sackmann, Monika Heiner, Ina Koch
COMCOM
2006
114views more  COMCOM 2006»
13 years 7 months ago
ImTCP: TCP with an inline measurement mechanism for available bandwidth
We introduce a novel mechanism for actively measuring available bandwidth along a network path. Instead of adding probe traffic to the network, the new mechanism exploits data pack...
Cao Le Thanh Man, Go Hasegawa, Masayuki Murata
BMCBI
2007
122views more  BMCBI 2007»
13 years 7 months ago
Dissecting complex transcriptional responses using pathway-level scores based on prior information
Background: The genomewide pattern of changes in mRNA expression measured using DNA microarrays is typically a complex superposition of the response of multiple regulatory pathway...
Harmen J. Bussemaker, Lucas D. Ward, André ...