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BMCBI
2010
106views more  BMCBI 2010»
13 years 10 months ago
A computational evaluation of over-representation of regulatory motifs in the promoter regions of differentially expressed genes
Background: Observed co-expression of a group of genes is frequently attributed to co-regulation by shared transcription factors. This assumption has led to the hypothesis that pr...
Guofeng Meng, Axel Mosig, Martin Vingron
BMCBI
2007
99views more  BMCBI 2007»
13 years 10 months ago
Identifying allosteric fluctuation transitions between different protein conformational states as applied to Cyclin Dependent Ki
Background: The mechanisms underlying protein function and associated conformational change are dominated by a series of local entropy fluctuations affecting the global structure ...
Jenny Gu, Philip E. Bourne
BMCBI
2007
182views more  BMCBI 2007»
13 years 10 months ago
Identifying regulatory targets of cell cycle transcription factors using gene expression and ChIP-chip data
Background: ChIP-chip data, which indicate binding of transcription factors (TFs) to DNA regions in vivo, are widely used to reconstruct transcriptional regulatory networks. Howev...
Wei-Sheng Wu, Wen-Hsiung Li, Bor-Sen Chen
JSA
2008
91views more  JSA 2008»
13 years 10 months ago
Using supplier locality in power-aware interconnects and caches in chip multiprocessors
Conventional snoopy-based chip multiprocessors take an aggressive approach broadcasting snoop requests to all nodes. In addition each node checks all received requests. This appro...
Ehsan Atoofian, Amirali Baniasadi
UMUAI
2008
144views more  UMUAI 2008»
13 years 10 months ago
Tag-based user modeling for social multi-device adaptive guides
This paper aims to demonstrate that the principles of adaptation and user modeling, especially social annotation, can be integrated fruitfully with those of the Web 2.0 paradigm a...
Francesca Carmagnola, Federica Cena, Luca Console,...