Background: To study complex biochemical reaction networks in living cells researchers more and more rely on databases and computational methods. In order to facilitate computatio...
Background: Biochemical investigations over the last decades have elucidated an increasingly complete image of the cellular metabolism. To derive a systems view for the regulation...
Gunnar Schramm, Marc Zapatka, Roland Eils, Rainer ...
— Models of biochemical reaction networks can be decomposed into a stoichiometric part and a kinetic part. The stoichiometric part describes the structural mass flows while the ...
Kinetic models for biochemical systems often comprise a large amount of coupled differential equations with species concentrations varying on different time scales. In this paper w...
Background: Software tools that model and simulate the dynamics of biological processes and systems are becoming increasingly important. Some of these tools offer sophisticated gr...