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» Adaptive Modeling of Biochemical Pathways
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ILP
2005
Springer
14 years 1 months ago
Machine Learning for Systems Biology
In this paper we survey work being conducted at Imperial College on the use of machine learning to build Systems Biology models of the effects of toxins on biochemical pathways. Se...
Stephen Muggleton
EVOW
2009
Springer
13 years 5 months ago
Evolutionary Approaches for Strain Optimization Using Dynamic Models under a Metabolic Engineering Perspective
One of the purposes of Systems Biology is the quantitative modeling of biochemical networks. In this effort, the use of dynamical mathematical models provides for powerful tools in...
Pedro Evangelista, Isabel Rocha, Eugénio C....
RECOMB
2005
Springer
14 years 1 months ago
Probabilistic in Silico Prediction of Protein-Peptide Interactions
Abstract. Peptide recognition modules (PRMs) are specialised compact protein domains that mediate many important protein-protein interactions. They are responsible for the assembly...
Wolfgang P. Lehrach, Dirk Husmeier, Christopher K....
ICML
2009
IEEE
14 years 8 months ago
Optimized expected information gain for nonlinear dynamical systems
This paper addresses the problem of active model selection for nonlinear dynamical systems. We propose a novel learning approach that selects the most informative subset of time-d...
Alberto Giovanni Busetto, Cheng Soon Ong, Joachim ...
BMCBI
2006
141views more  BMCBI 2006»
13 years 7 months ago
Visual setup of logical models of signaling and regulatory networks with ProMoT
Background: The analysis of biochemical networks using a logical (Boolean) description is an important approach in Systems Biology. Recently, new methods have been proposed to ana...
Julio Saez-Rodriguez, Sebastian Mirschel, Rebecca ...