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BMCBI
2008
130views more  BMCBI 2008»
13 years 7 months ago
FAF-Drugs2: Free ADME/tox filtering tool to assist drug discovery and chemical biology projects
Background: Drug discovery and chemical biology are exceedingly complex and demanding enterprises. In recent years there are been increasing awareness about the importance of pred...
David Lagorce, Olivier Sperandio, Hervé Gal...
BMCBI
2008
135views more  BMCBI 2008»
13 years 7 months ago
Ab-origin: an enhanced tool to identify the sourcing gene segments in germline for rearranged antibodies
Background: In the adaptive immune system, variable regions of immunoglobulin (IG) are encoded by random recombination of variable (V), diversity (D), and joining (J) gene segment...
Xiaojing Wang, Di Wu, SiYuan Zheng, Jing Sun, Lin ...
CAD
2006
Springer
13 years 7 months ago
An efficient, error-bounded approximation algorithm for simulating quasi-statics of complex linkages
Design and analysis of articulated mechanical structures, commonly referred to as linkages, is an integral part of any CAD/CAM system. The most common approaches formulate the pro...
Stephane Redon, Ming C. Lin
BMCBI
2007
111views more  BMCBI 2007»
13 years 7 months ago
MotifCombinator: a web-based tool to search for combinations of cis-regulatory motifs
Background: A combination of multiple types of transcription factors and cis-regulatory elements is often required for gene expression in eukaryotes, and the combinatorial regulat...
Mamoru Kato, Tatsuhiko Tsunoda
JSAC
2006
165views more  JSAC 2006»
13 years 7 months ago
ALPi: A DDoS Defense System for High-Speed Networks
Distributed denial-of-service (DDoS) attacks pose a significant threat to the Internet. Most solutions proposed to-date face scalability problems as the size and speed of the netwo...
P. E. Ayres, H. Sun, H. Jonathan Chao, Wing Cheong...