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BMCBI
2010
105views more  BMCBI 2010»
13 years 7 months ago
Subdivision of the MDR superfamily of medium-chain dehydrogenases/reductases through iterative hidden Markov model refinement
Background: The Medium-chain Dehydrogenases/Reductases (MDR) form a protein superfamily whose size and complexity defeats traditional means of subclassification; it currently has ...
Joel Hedlund, Hans Jörnvall, Bengt Persson
BMCBI
2007
105views more  BMCBI 2007»
13 years 7 months ago
HoxPred: automated classification of Hox proteins using combinations of generalised profiles
Background: Correct identification of individual Hox proteins is an essential basis for their study in diverse research fields. Common methods to classify Hox proteins focus on th...
Morgane Thomas-Chollier, Luc Leyns, Valérie...
BMCBI
2010
129views more  BMCBI 2010»
13 years 7 months ago
The LabelHash Algorithm for Substructure Matching
Background: There is an increasing number of proteins with known structure but unknown function. Determining their function would have a significant impact on understanding diseas...
Mark Moll, Drew H. Bryant, Lydia E. Kavraki
BMCBI
2008
103views more  BMCBI 2008»
13 years 7 months ago
TOPS++FATCAT: Fast flexible structural alignment using constraints derived from TOPS+ Strings Model
Background: Protein structure analysis and comparison are major challenges in structural bioinformatics. Despite the existence of many tools and algorithms, very few of them have ...
Mallika Veeramalai, Yuzhen Ye, Adam Godzik
BMCBI
2008
144views more  BMCBI 2008»
13 years 7 months ago
PDTD: a web-accessible protein database for drug target identification
Background: Target identification is important for modern drug discovery. With the advances in the development of molecular docking, potential binding proteins may be discovered b...
Zhenting Gao, Honglin Li, Hailei Zhang, Xiaofeng L...