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BMCBI
2008
130views more  BMCBI 2008»
13 years 9 months ago
FAF-Drugs2: Free ADME/tox filtering tool to assist drug discovery and chemical biology projects
Background: Drug discovery and chemical biology are exceedingly complex and demanding enterprises. In recent years there are been increasing awareness about the importance of pred...
David Lagorce, Olivier Sperandio, Hervé Gal...
BMCBI
2008
78views more  BMCBI 2008»
13 years 9 months ago
Genome Environment Browser (GEB): a dynamic browser for visualising high-throughput experimental data in the context of genome f
Background: There is accumulating evidence that the milieu of repeat elements and other nongenic sequence features at a given chromosomal locus, here defined as the genome environ...
Derek Huntley, Y. Amy Tang, Tatyana B. Nesterova, ...
ENTCS
2008
142views more  ENTCS 2008»
13 years 9 months ago
An Open System Operational Semantics for an Object-Oriented and Component-Based Language
Object orientation and component-based development have both proven useful for the elaboration of open distributed systems. These paradigms are offered by the Creol language. Creo...
Jasmin Christian Blanchette, Olaf Owe
BMCBI
2006
179views more  BMCBI 2006»
13 years 9 months ago
Multiscale Hy3S: Hybrid stochastic simulation for supercomputers
Background: Stochastic simulation has become a useful tool to both study natural biological systems and design new synthetic ones. By capturing the intrinsic molecular fluctuation...
Howard Salis, Vassilios Sotiropoulos, Yiannis N. K...
BMCBI
2006
156views more  BMCBI 2006»
13 years 9 months ago
Score-based prediction of genomic islands in prokaryotic genomes using hidden Markov models
Background: Horizontal gene transfer (HGT) is considered a strong evolutionary force shaping the content of microbial genomes in a substantial manner. It is the difference in spee...
Stephan Waack, Oliver Keller, Roman Asper, Thomas ...