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» Advances in constrained clustering
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BMCBI
2008
141views more  BMCBI 2008»
13 years 10 months ago
Discovering functional interaction patterns in protein-protein interaction networks
Background: In recent years, a considerable amount of research effort has been directed to the analysis of biological networks with the availability of genome-scale networks of ge...
Mehmet E. Turanalp, Tolga Can
BMCBI
2007
160views more  BMCBI 2007»
13 years 10 months ago
Identifying protein complexes directly from high-throughput TAP data with Markov random fields
Background: Predicting protein complexes from experimental data remains a challenge due to limited resolution and stochastic errors of high-throughput methods. Current algorithms ...
Wasinee Rungsarityotin, Roland Krause, Arno Sch&ou...
BMCBI
2006
144views more  BMCBI 2006»
13 years 10 months ago
Development and implementation of an algorithm for detection of protein complexes in large interaction networks
Background: After complete sequencing of a number of genomes the focus has now turned to proteomics. Advanced proteomics technologies such as two-hybrid assay, mass spectrometry e...
Md. Altaf-Ul-Amin, Yoko Shinbo, Kenji Mihara, Ken ...
BMCBI
2006
155views more  BMCBI 2006»
13 years 10 months ago
AffyMiner: mining differentially expressed genes and biological knowledge in GeneChip microarray data
Background: DNA microarrays are a powerful tool for monitoring the expression of tens of thousands of genes simultaneously. With the advance of microarray technology, the challeng...
Guoqing Lu, The V. Nguyen, Yuannan Xia, Michael Fr...
BMCBI
2006
159views more  BMCBI 2006»
13 years 10 months ago
EVEREST: automatic identification and classification of protein domains in all protein sequences
Background: Proteins are comprised of one or several building blocks, known as domains. Such domains can be classified into families according to their evolutionary origin. Wherea...
Elon Portugaly, Amir Harel, Nathan Linial, Michal ...