Background: During the past decades, research and development in drug discovery have attracted much attention and efforts. However, only 324 drug targets are known for clinical dr...
We have employed various sequence alignment algorithms and scoring techniques to determine whether current computational tools accurately predict genes that will be off-targeted b...
Amanda Birmingham, Emily M. Anderson, William S. M...
This paper presents the PLANMINE sequence mining algorithm to extract patterns of events that predict failures in databases of plan executions. New techniques were needed because p...
Mohammed Javeed Zaki, Neal Lesh, Mitsunori Ogihara
A method is presented that uses b-strand interactions to predict the parallel right-handed b-helix super-secondary structural motif in protein sequences. A program called BetaWrap...
Phil Bradley, Lenore Cowen, Matthew Menke, Jonatha...
The accurate prediction of enzyme catalytic sites remains an open problem in bioinformatics. Recently, several structure-based methods have become popular; however, few robust seq...