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» Agent-based protein structure prediction
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IEAAIE
2010
Springer
15 years 2 months ago
S.cerevisiae Complex Function Prediction with Modular Multi-Relational Framework
Gene functions is an essential knowledge for understanding how metabolism works and designing treatments for solving malfunctions. The Modular Multi-Relational Framework (MMRF) is ...
Beatriz García Jiménez, Agapito Lede...
GCB
1998
Springer
78views Biometrics» more  GCB 1998»
15 years 8 months ago
Computational approaches to identify Leucine Zippers
The leucine zipper is a dimerization domain occurring mostly in regulatory and thus in many oncogenic proteins. The leucine repeat in the sequence has been traditionally used for ...
Erich Bornberg-Bauer
ICML
2007
IEEE
16 years 5 months ago
An integrated approach to feature invention and model construction for drug activity prediction
We present a new machine learning approach for 3D-QSAR, the task of predicting binding affinities of molecules to target proteins based on 3D structure. Our approach predicts bind...
David Page, Jesse Davis, Soumya Ray, Vítor ...
GCB
2005
Springer
98views Biometrics» more  GCB 2005»
15 years 10 months ago
Composite Module Analyst: A Fitness-Based Tool for Prediction of Transcription Regulation
: Functionally related genes involved in the same molecular-genetic, biochemical, or physiological process are often regulated coordinately Such regulation is provided by precisely...
Alexander E. Kel, Tatiana Konovalova, Tagir Valeev...
BMCBI
2006
108views more  BMCBI 2006»
15 years 4 months ago
NOXclass: prediction of protein-protein interaction types
Background: Structural models determined by X-ray crystallography play a central role in understanding protein-protein interactions at the molecular level. Interpretation of these...
Hongbo Zhu, Francisco S. Domingues, Ingolf Sommer,...