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BMCBI
2008
166views more  BMCBI 2008»
13 years 7 months ago
Biclustering via optimal re-ordering of data matrices in systems biology: rigorous methods and comparative studies
Background: The analysis of large-scale data sets via clustering techniques is utilized in a number of applications. Biclustering in particular has emerged as an important problem...
Peter A. DiMaggio Jr., Scott R. McAllister, Christ...
BMCBI
2008
172views more  BMCBI 2008»
13 years 7 months ago
Compo: composite motif discovery using discrete models
Background: Computational discovery of motifs in biomolecular sequences is an established field, with applications both in the discovery of functional sites in proteins and regula...
Geir Kjetil Sandve, Osman Abul, Finn Drablø...
BMCBI
2008
104views more  BMCBI 2008»
13 years 7 months ago
Comparison of methods for estimating the nucleotide substitution matrix
Background: The nucleotide substitution rate matrix is a key parameter of molecular evolution. Several methods for inferring this parameter have been proposed, with different math...
Maribeth Oscamou, Daniel McDonald, Von Bing Yap, G...
BMCBI
2008
143views more  BMCBI 2008»
13 years 7 months ago
catmap: Case-control And TDT Meta-Analysis Package
Background: Risk for complex disease is thought to be controlled by multiple genetic risk factors, each with small individual effects. Meta-analyses of several independent studies...
Kristin K. Nicodemus
BMCBI
2008
110views more  BMCBI 2008»
13 years 7 months ago
Enhancing the prediction of protein pairings between interacting families using orthology information
Background: It has repeatedly been shown that interacting protein families tend to have similar phylogenetic trees. These similarities can be used to predicting the mapping betwee...
José M. G. Izarzugaza, David de Juan, Carle...
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