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BMCBI
2010
112views more  BMCBI 2010»
13 years 6 months ago
In silico fragmentation for computer assisted identification of metabolite mass spectra
Background: Mass spectrometry has become the analytical method of choice in metabolomics research. The identification of unknown compounds is the main bottleneck. In addition to t...
Sebastian Wolf, Stephan Schmidt, Matthias Mül...
BMCBI
2007
109views more  BMCBI 2007»
13 years 6 months ago
A cis-regulatory logic simulator
Background: A major goal of computational studies of gene regulation is to accurately predict the expression of genes based on the cis-regulatory content of their promoters. The d...
Robert D. Zeigler, Jason Gertz, Barak A. Cohen
BMCBI
2006
119views more  BMCBI 2006»
13 years 6 months ago
Utilization of two sample t-test statistics from redundant probe sets to evaluate different probe set algorithms in GeneChip stu
Background: The choice of probe set algorithms for expression summary in a GeneChip study has a great impact on subsequent gene expression data analysis. Spiked-in cRNAs with know...
Zihua Hu, Gail R. Willsky
EXPERT
2006
156views more  EXPERT 2006»
13 years 6 months ago
Computational Models of Ethical Reasoning: Challenges, Initial Steps, and Future Directions
on abstract principles that you can't easily apply in a formal, deductive fashion. So, the favorite tools of logicians and mathematicians, such as firstorder logic, aren'...
Bruce M. McLaren
BMCBI
2005
196views more  BMCBI 2005»
13 years 6 months ago
Chemistry in Bioinformatics
Chemical information is now seen as critical for most areas of life sciences. But unlike Bioinformatics, where data is Openly available and freely re-usable, most chemical informa...
Peter Murray-Rust, John B. O. Mitchell, Henry S. R...