Background: With the current technological advances in high-throughput biology, the necessity to develop tools that help to analyse the massive amount of data being generated is e...
Maciej Paszkowski-Rogacz, Mikolaj Slabicki, M. Ter...
Background: The analysis of high-throughput screening data sets is an expanding field in bioinformatics. Highthroughput screens by RNAi generate large primary data sets which need...
Background: S. cerevisiae, A. thaliana and M. musculus are well-studied organisms in biology and the sequencing of their genomes was completed many years ago. It is still a challe...
Leander Schietgat, Celine Vens, Jan Struyf, Hendri...
Background: Illumina's second-generation sequencing platform is playing an increasingly prominent role in modern DNA and RNA sequencing efforts. However, rapid, simple, stand...
Murray P. Cox, Daniel A. Peterson, Patrick J. Bigg...
Background: Data generated using `omics' technologies are characterized by high dimensionality, where the number of features measured per subject vastly exceeds the number of...
Yu Guo, Armin Graber, Robert N. McBurney, Raji Bal...