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» Algorithms for Challenging Motif Problems
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BMCBI
2008
128views more  BMCBI 2008»
13 years 8 months ago
Pairwise covariance adds little to secondary structure prediction but improves the prediction of non-canonical local structure
Background: Amino acid sequence probability distributions, or profiles, have been used successfully to predict secondary structure and local structure in proteins. Profile models ...
Christopher Bystroff, Bobbie-Jo M. Webb-Robertson
BMCBI
2008
98views more  BMCBI 2008»
13 years 8 months ago
MTAP: The Motif Tool Assessment Platform
Background: In recent years, substantial effort has been applied to de novo regulatory motif discovery. At this time, more than 150 software tools exist to detect regulatory bindi...
Daniel Quest, Kathryn Dempsey, Mohammad Shafiullah...
KDD
2010
ACM
199views Data Mining» more  KDD 2010»
13 years 11 months ago
Online discovery and maintenance of time series motifs
The detection of repeated subsequences, time series motifs, is a problem which has been shown to have great utility for several higher-level data mining algorithms, including clas...
Abdullah Mueen, Eamonn J. Keogh
NN
2006
Springer
13 years 8 months ago
Self-organizing neural networks to support the discovery of DNA-binding motifs
Identification of the short DNA sequence motifs that serve as binding targets for transcription factors is an important challenge in bioinformatics. Unsupervised techniques from t...
Shaun Mahony, Panayiotis V. Benos, Terry J. Smith,...
CSB
2004
IEEE
158views Bioinformatics» more  CSB 2004»
13 years 11 months ago
Algorithms for Association Study Design Using a Generalized Model of Haplotype Conservation
There is considerable interest in computational methods to assist in the use of genetic polymorphism data for locating disease-related genes. Haplotypes, contiguous sets of correl...
Russell Schwartz