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BMCBI
2010
13 years 9 months ago
2010
Background: Detecting epistatic interactions associated with complex and common diseases can help to improve prevention, diagnosis and treatment of these diseases. With the develo...
BMCBI
2007
13 years 9 months ago
2007
Background: Since real time PCR was first developed, several approaches to estimating the initial quantity of template in an RT-PCR reaction have been tried. While initially only ...
BMCBI
2007
13 years 9 months ago
2007
Background: In general, the construction of trees is based on sequence alignments. This procedure, however, leads to loss of informationwhen parts of sequence alignments (for inst...
BMCBI
2008
13 years 9 months ago
2008
Background: Microarray experiments generate vast amounts of data. The functional context of differentially expressed genes can be assessed by querying the Gene Ontology (GO) datab...
BMCBI
2008
13 years 9 months ago
2008
Background: Aligning homologous non-coding RNAs (ncRNAs) correctly in terms of sequence and structure is an unresolved problem, due to both mathematical complexity and imperfect s...