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BMCBI
2006
13 years 9 months ago
2006
We investigate the application of hierarchical classification schemes to the annotation of gene function based on several characteristics of protein sequences including phylogenic ...
BMCBI
2006
13 years 9 months ago
2006
Background: The identification of chromosomal homology will shed light on such mysteries of genome evolution as DNA duplication, rearrangement and loss. Several approaches have be...
BMCBI
2006
13 years 9 months ago
2006
Background: There have been many algorithms and software programs implemented for the inference of multiple sequence alignments of protein and DNA sequences. The "true" ...
BMCBI
2006
13 years 9 months ago
2006
Background: The small sample sizes often used for microarray experiments result in poor estimates of variance if each gene is considered independently. Yet accurately estimating v...
BMCBI
2006
13 years 9 months ago
2006
Background: Horizontal gene transfer (HGT) has allowed bacteria to evolve many new capabilities. Because transferred genes perform many medically important functions, such as conf...