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RECOMB
2005
Springer
14 years 8 months ago
Efficient Algorithms for Detecting Signaling Pathways in Protein Interaction Networks
Abstract. The interpretation of large-scale protein network data depends on our ability to identify significant sub-structures in the data, a computationally intensive task. Here w...
Jacob Scott, Trey Ideker, Richard M. Karp, Roded S...
BMCBI
2011
13 years 2 months ago
The PathOlogist: An Automated Tool for Pathway-Centric Analysis
Background: The PathOlogist is a new tool designed to transform large sets of gene expression data into quantitative descriptors of pathway-level behavior. The tool aims to provid...
Sharon I. Greenblum, Sol Efroni, Carl F. Schaefer,...
NAR
2010
123views more  NAR 2010»
13 years 2 months ago
Discovering causal signaling pathways through gene-expression patterns
High-throughput gene-expression studies result in lists of differentially expressed genes. Most current meta-analyses of these gene lists include searching for significant members...
Jignesh R. Parikh, Bertram Klinger, Yu Xia, Jarrod...
ESANN
2008
13 years 9 months ago
A method for robust variable selection with significance assessment
Our goal is proposing an unbiased framework for gene expression analysis based on variable selection combined with a significance assessment step. We start by discussing the need ...
Annalisa Barla, Sofia Mosci, Lorenzo Rosasco, Ales...
MICCAI
2004
Springer
14 years 8 months ago
Cervical Cancer Detection Using SVM Based Feature Screening
We present a novel feature screening algorithm by deriving relevance measures from the decision boundary of Support Vector Machines. It alleviates the "independence" assu...
Jiayong Zhang, Yanxi Liu