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BMCBI
2010
105views more  BMCBI 2010»
13 years 7 months ago
A knowledge-guided strategy for improving the accuracy of scoring functions in binding affinity prediction
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
Tiejun Cheng, Zhihai Liu, Renxiao Wang
BMCBI
2008
137views more  BMCBI 2008»
13 years 7 months ago
VennMaster: Area-proportional Euler diagrams for functional GO analysis of microarrays
Background: Microarray experiments generate vast amounts of data. The functional context of differentially expressed genes can be assessed by querying the Gene Ontology (GO) datab...
Hans A. Kestler, André Müller, Johann ...
BMCBI
2010
178views more  BMCBI 2010»
13 years 7 months ago
Applications of a formal approach to decipher discrete genetic networks
Background: A growing demand for tools to assist the building and analysis of biological networks exists in systems biology. We argue that the use of a formal approach is relevant...
Fabien Corblin, Eric Fanchon, Laurent Trilling
BMCBI
2007
158views more  BMCBI 2007»
13 years 7 months ago
MetaLook: a 3D visualisation software for marine ecological genomics
Background: Marine ecological genomics can be defined as the application of genomic sciences to understand the structure and function of marine ecosystems. In this field of resear...
Thierry Lombardot, Renzo Kottmann, Gregory Giulian...
BMCBI
2007
174views more  BMCBI 2007»
13 years 7 months ago
ESTuber db: an online database for Tuber borchii EST sequences
Background: The ESTuber database (http://www.itb.cnr.it/estuber) includes 3,271 Tuber borchii expressed sequence tags (EST). The dataset consists of 2,389 sequences from an in-hou...
Barbara Lazzari, Andrea Caprera, Cristian Cosentin...