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BMCBI
2010
96views more  BMCBI 2010»
15 years 3 months ago
ModuleOrganizer: detecting modules in families of transposable elements
Background: Most known eukaryotic genomes contain mobile copied elements called transposable elements. In some species, these elements account for the majority of the genome seque...
Sébastien Tempel, Christine Rousseau, Fariz...
BMCBI
2008
169views more  BMCBI 2008»
15 years 3 months ago
CompMoby: Comparative MobyDick for detection of cis-regulatory motifs
Background: The regulation of gene expression is complex and occurs at many levels, including transcriptional and post-transcriptional, in metazoans. Transcriptional regulation is...
Christina Chaivorapol, Collin Melton, Grace Wei, R...
BMCBI
2007
99views more  BMCBI 2007»
15 years 3 months ago
Flexible mapping of homology onto structure with Homolmapper
Background: Over the past decade, a number of tools have emerged for the examination of homology relationships among protein sequences in a structural context. Most recent softwar...
Nathan C. Rockwell, J. Clark Lagarias
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BMCBI
2008
178views more  BMCBI 2008»
15 years 3 months ago
A discriminative method for protein remote homology detection and fold recognition combining Top-n-grams and latent semantic ana
Background: Protein remote homology detection and fold recognition are central problems in bioinformatics. Currently, discriminative methods based on support vector machine (SVM) ...
Bin Liu, Xiaolong Wang, Lei Lin, Qiwen Dong, Xuan ...
BMCBI
2008
142views more  BMCBI 2008»
15 years 3 months ago
Strategies for measuring evolutionary conservation of RNA secondary structures
Background: Evolutionary conservation of RNA secondary structure is a typical feature of many functional non-coding RNAs. Since almost all of the available methods used for predic...
Andreas R. Gruber, Stephan H. F. Bernhart, Ivo L. ...