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BMCBI
2010
116views more  BMCBI 2010»
13 years 7 months ago
FiGS: a filter-based gene selection workbench for microarray data
Background: The selection of genes that discriminate disease classes from microarray data is widely used for the identification of diagnostic biomarkers. Although various gene sel...
Taeho Hwang, Choong-Hyun Sun, Taegyun Yun, Gwan-Su...
BMCBI
2010
116views more  BMCBI 2010»
13 years 7 months ago
Optimization algorithms for functional deimmunization of therapeutic proteins
Background: To develop protein therapeutics from exogenous sources, it is necessary to mitigate the risks of eliciting an anti-biotherapeutic immune response. A key aspect of the ...
Andrew S. Parker, Wei Zheng, Karl E. Griswold, Chr...
BMCBI
2010
153views more  BMCBI 2010»
13 years 7 months ago
Starr: Simple Tiling ARRay analysis of Affymetrix ChIP-chip data
Background: Chromatin immunoprecipitation combined with DNA microarrays (ChIP-chip) is an assay used for investigating DNA-protein-binding or post-translational chromatin/histone ...
Benedikt Zacher, Pei Fen Kuan, Achim Tresch
BMCBI
2010
94views more  BMCBI 2010»
13 years 7 months ago
A high-throughput pipeline for the design of real-time PCR signatures
Background: Pathogen diagnostic assays based on polymerase chain reaction (PCR) technology provide high sensitivity and specificity. However, the design of these diagnostic assays...
Ravi Vijaya Satya, Kamal Kumar, Nela Zavaljevski, ...
BMCBI
2010
133views more  BMCBI 2010»
13 years 7 months ago
Translog, a web browser for studying the expression divergence of homologous genes
Background: Increasing amount of data from comparative genomics, and newly developed technologies producing accurate gene expression data facilitate the study of the expression di...
Xianjun Dong, Altuna Akalin, Yogita Sharma, Boris ...