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BMCBI
2007
97views more  BMCBI 2007»
13 years 7 months ago
In situ analysis of cross-hybridisation on microarrays and the inference of expression correlation
Background: Microarray co-expression signatures are an important tool for studying gene function and relations between genes. In addition to genuine biological co-expression, corr...
Tineke Casneuf, Yves Van de Peer, Wolfgang Huber
BMCBI
2007
89views more  BMCBI 2007»
13 years 7 months ago
Primique: automatic design of specific PCR primers for each sequence in a family
Background: In many contexts, researchers need specific primers for all sequences in a family such that each primer set amplifies only its target sequence and none of the others, ...
Jakob Fredslund, Mette Lange
BMCBI
2007
117views more  BMCBI 2007»
13 years 7 months ago
DNA-based watermarks using the DNA-Crypt algorithm
Background: The aim of this paper is to demonstrate the application of watermarks based on DNA sequences to identify the unauthorized use of genetically modified organisms (GMOs) ...
Dominik Heider, Angelika Barnekow
BMCBI
2007
162views more  BMCBI 2007»
13 years 7 months ago
Three-Dimensional Phylogeny Explorer: Distinguishing paralogs, lateral transfer, and violation of "molecular clock" assumption w
Background: Construction and interpretation of phylogenetic trees has been a major research topic for understanding the evolution of genes. Increases in sequence data and complexi...
Namshin Kim, Christopher Lee
BMCBI
2007
152views more  BMCBI 2007»
13 years 7 months ago
Bioinformatic identification of novel putative photoreceptor specific cis-elements
Background: Cell specific gene expression is largely regulated by different combinations of transcription factors that bind cis-elements in the upstream promoter sequence. However...
Charles G. Danko, Vera A. McIlvain, Maochun Qin, B...