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» Aligning Alignments
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BMCBI
2007
134views more  BMCBI 2007»
13 years 10 months ago
Efficient pairwise RNA structure prediction using probabilistic alignment constraints in Dynalign
Background: Joint alignment and secondary structure prediction of two RNA sequences can significantly improve the accuracy of the structural predictions. Methods addressing this p...
Arif Ozgun Harmanci, Gaurav Sharma, David H. Mathe...
JCDL
2006
ACM
176views Education» more  JCDL 2006»
14 years 4 months ago
A hierarchical, HMM-based automatic evaluation of OCR accuracy for a digital library of books
A number of projects are creating searchable digital libraries of printed books. These include the Million Book Project, the Google Book project and similar efforts from Yahoo an...
Shaolei Feng, R. Manmatha
BMCBI
2007
120views more  BMCBI 2007»
13 years 10 months ago
Phylo-mLogo: an interactive and hierarchical multiple-logo visualization tool for alignment of many sequences
Background: When aligning several hundreds or thousands of sequences, such as epidemic virus sequences or homologous/orthologous sequences of some big gene families, to reconstruc...
Arthur Chun-Chieh Shih, D. T. Lee, Chin-Lin Peng, ...
BMCBI
2008
124views more  BMCBI 2008»
13 years 10 months ago
Alignment of protein structures in the presence of domain motions
Background: Structural alignment is an important step in protein comparison. Well-established methods exist for solving this problem under the assumption that the structures under...
Roberto Mosca, Barbara Brannetti, Thomas R. Schnei...
BMCBI
2008
113views more  BMCBI 2008»
13 years 10 months ago
Investigating selection on viruses: a statistical alignment approach
Background: Two problems complicate the study of selection in viral genomes: Firstly, the presence of genes in overlapping reading frames implies that selection in one reading fra...
Saskia de Groot, Thomas Mailund, Gerton Lunter, Jo...