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» Aligning Two Fragmented Sequences
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ECML
2006
Springer
14 years 1 months ago
PAC-Learning of Markov Models with Hidden State
The standard approach for learning Markov Models with Hidden State uses the Expectation-Maximization framework. While this approach had a significant impact on several practical ap...
Ricard Gavaldà, Philipp W. Keller, Joelle P...
RECOMB
2000
Springer
14 years 1 months ago
Contig selection in physical mapping
In physical mapping, one orders a set of genetic landmarks or a library of cloned fragments of DNA according to their position in the genome. Our approach to physical mapping divi...
Steffen Heber, Jens Stoye, Jörg D. Hoheisel, ...
ICPPW
2009
IEEE
13 years 7 months ago
A Scalable Parallel Approach for Peptide Identification from Large-Scale Mass Spectrometry Data
Identifying peptides, which are short polymeric chains of amino acid residues in a protein sequence, is of fundamental importance in systems biology research. The most popular appr...
Gaurav Ramesh Kulkarni, Ananth Kalyanaraman, Willi...
BMCBI
2008
93views more  BMCBI 2008»
13 years 10 months ago
Homology modelling of protein-protein complexes: a simple method and its possibilities and limitations
Background: Structure-based computational methods are needed to help identify and characterize protein-protein complexes and their function. For individual proteins, the most succ...
Guillaume Launay, Thomas Simonson
BMCBI
2007
59views more  BMCBI 2007»
13 years 10 months ago
Environment specific substitution tables for thermophilic proteins
Background: Thermophilic organisms are able to live at high temperatures ranging from 50 to > 100°C. Their proteins must be sufficiently stable to function under these extreme...
K. Mizuguchi, M. Sele, Maria Vittoria Cubellis