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» Aligning Two Fragmented Sequences
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BIBE
2005
IEEE
124views Bioinformatics» more  BIBE 2005»
14 years 3 months ago
Approximate Global Alignment of Sequences
We propose two novel dynamic programming (DP) methods that solve the the approximate bounded and unbounded global alignment problems for biological sequences. Our first method so...
Tamer Kahveci, Venkatakrishnan Ramaswamy, Han Tao,...
CIBCB
2007
IEEE
14 years 4 months ago
Overestimation for Multiple Sequence Alignment
Abstract— Multiple sequence alignment is an important problem in computational biology. A-star is an algorithm that can be used to find exact alignments. We present a simple mod...
Tristan Cazenave
NAR
2010
140views more  NAR 2010»
13 years 4 months ago
GUIDANCE: a web server for assessing alignment confidence scores
Evaluating the accuracy of multiple sequence alignment (MSA) is critical for virtually every comparative sequence analysis that uses an MSA as input. Here we present the GUIDANCE ...
Osnat Penn, Eyal Privman, Haim Ashkenazy, Giddy La...
BMCBI
2005
158views more  BMCBI 2005»
13 years 9 months ago
Automated generation of heuristics for biological sequence comparison
Background: Exhaustive methods of sequence alignment are accurate but slow, whereas heuristic approaches run quickly, but their complexity makes them more difficult to implement. ...
Guy St. C. Slater, Ewan Birney
BIBE
2005
IEEE
126views Bioinformatics» more  BIBE 2005»
14 years 3 months ago
Suboptimal Alignments Improve the Detection of Weak Homologs in Sequence Database Searches
PSI-BLAST remains one of the popular tools for searching remote homologs in sequence databases. We recently demonstrated that hybrid alignment can function as the alignment core f...
Yuheng Li, Mario Lauria, Ralf Bundschuh