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» Alignment of Non-Overlapping Sequences
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PPSN
2004
Springer
14 years 4 months ago
An Evolutionary Algorithm for the Maximum Weight Trace Formulation of the Multiple Sequence Alignment Problem
Abstract. The multiple sequence alignment problem (MSA) can be reformulated as the problem of finding a maximum weight trace in an alignment graph, which is derived from all pairw...
Gabriele Koller, Günther R. Raidl
BMCBI
2005
93views more  BMCBI 2005»
13 years 10 months ago
Multiple sequence alignment accuracy and evolutionary distance estimation
Background: Sequence alignment is a common tool in bioinformatics and comparative genomics. It is generally assumed that multiple sequence alignment yields better results than pai...
Michael S. Rosenberg
BIB
2006
141views more  BIB 2006»
13 years 10 months ago
Statistical significance in biological sequence analysis
One of the major goals of computational sequence analysis is to find sequence similarities, which could serve as evidence of structural and functional conservation, as well as of ...
Alexander Yu. Mitrophanov, Mark Borodovsky
BMCBI
2007
156views more  BMCBI 2007»
13 years 11 months ago
Accuracy of structure-based sequence alignment of automatic methods
Background: Accurate sequence alignments are essential for homology searches and for building three-dimensional structural models of proteins. Since structure is better conserved ...
Changhoon Kim, Byungkook Lee
ICASSP
2008
IEEE
14 years 5 months ago
Probabilistic structural alignment of RNA sequences
We propose an algorithm for estimating the common secondary structure, alignment, and posterior base pairing probabilities for two RNA sequences. A definition of structural align...
Arif Ozgun Harmanci, Gaurav Sharma, David H. Mathe...