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» Alignment of Non-Overlapping Sequences
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ISMB
1997
15 years 4 months ago
Increasing Consensus Accuracy in DNA Fragment Assemblies by Incorporating Fluorescent Trace Representations
We present a new method for determining the consensus sequence in DNA fragment assemblies. The new method, Trace-Evidence, directly incorporates aligned ABI trace information into...
Carolyn F. Allex, Schuyler F. Baldwin, Jude W. Sha...
IJCBDD
2008
141views more  IJCBDD 2008»
15 years 2 months ago
CLUSS2: an alignment-independent algorithm for clustering protein families with multiple biological functions
: CLUSS is an algorithm proposed for clustering both alignable and non-alignable protein sequences. However, CLUSS tends to be ineffective on protein datasets that include a large ...
Abdellali Kelil, Shengrui Wang, Ryszard Brzezinski
BMCBI
2004
208views more  BMCBI 2004»
15 years 2 months ago
Using 3D Hidden Markov Models that explicitly represent spatial coordinates to model and compare protein structures
Background: Hidden Markov Models (HMMs) have proven very useful in computational biology for such applications as sequence pattern matching, gene-finding, and structure prediction...
Vadim Alexandrov, Mark Gerstein
ISMB
1993
15 years 4 months ago
Detection of Correlations in tRNA Sequences with Structural Implications
Using a flexible representation of biological sequences, we have performed a comparative analysis of 1208 known tRNA sequences. We believe we our technique is a more sensitive met...
Tod M. Klingler, Douglas L. Brutlag
151
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BMCBI
2006
166views more  BMCBI 2006»
15 years 2 months ago
SEQOPTICS: a protein sequence clustering system
Background: Protein sequence clustering has been widely used as a part of the analysis of protein structure and function. In most cases single linkage or graph-based clustering al...
Yonghui Chen, Kevin D. Reilly, Alan P. Sprague, Zh...