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» Alignment of Non-Overlapping Sequences
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BMCBI
2006
103views more  BMCBI 2006»
13 years 10 months ago
Domain-based small molecule binding site annotation
Background: Accurate small molecule binding site information for a protein can facilitate studies in drug docking, drug discovery and function prediction, but small molecule bindi...
Kevin A. Snyder, Howard J. Feldman, Michel Dumonti...
BMCBI
2005
108views more  BMCBI 2005»
13 years 9 months ago
SplitTester: software to identify domains responsible for functional divergence in protein family
Background: Many protein families have undergone functional divergence after gene duplications such that current subgroups of the family carry out overlapping but distinct biologi...
Xiang Gao, Kent Vander Velden, Daniel F. Voytas, X...
BMCBI
2005
94views more  BMCBI 2005»
13 years 9 months ago
Measuring similarities between transcription factor binding sites
Background: Collections of transcription factor binding profiles (Transfac, Jaspar) are essential to identify regulatory elements in DNA sequences. Subsets of highly similar profi...
Szymon M. Kielbasa, Didier Gonze, Hanspeter Herzel
ISMB
1997
13 years 11 months ago
Standardized Representations of the Literature: Combining Diverse Sources of Ribosomal Data
We are building a knowledge base (KB) of published structural data on the 30s ribosomal subunit in prokaryotes. Our KB is distinguished by a standardized representation of biologi...
Russ B. Altman, Neil F. Abernethy, Richard O. Chen
BMCBI
2007
136views more  BMCBI 2007»
13 years 10 months ago
Genomorama: genome visualization and analysis
Background: The ability to visualize genomic features and design experimental assays that can target specific regions of a genome is essential for modern biology. To assist in the...
Jason D. Gans, Murray Wolinsky