Scientific data offers some of the most interesting challenges in data integration today. Scientific fields evolve rapidly and accumulate masses of observational and experiment...
Partha Pratim Talukdar, Zachary G. Ives, Fernando ...
Background: Mass Spectrometry coupled to Liquid Chromatography (LC-MS) is commonly used to analyze the protein content of biological samples in large scale studies. The data resul...
Ole Schulz-Trieglaff, Nico Pfeifer, Clemens Gr&oum...
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
Background: The post-genomic era is characterised by a torrent of biological information flooding the public databases. As a direct consequence, similarity searches starting with ...
Anne Friedrich, Raymond Ripp, Nicolas Garnier, Emm...
Phylogenetic analyses are central to many research areas in biology and typically involve the identification of homologous sequences, their multiple alignment, the phylogenetic re...