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» Alignments of RNA Structures
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BMCBI
2007
114views more  BMCBI 2007»
13 years 8 months ago
Large scale statistical inference of signaling pathways from RNAi and microarray data
Background: The advent of RNA interference techniques enables the selective silencing of biologically interesting genes in an efficient way. In combination with DNA microarray tec...
Holger Fröhlich, Mark Fellmann, Holger Sü...
BMCBI
2007
135views more  BMCBI 2007»
13 years 8 months ago
Sequence similarity is more relevant than species specificity in probabilistic backtranslation
Background: Backtranslation is the process of decoding a sequence of amino acids into the corresponding codons. All synthetic gene design systems include a backtranslation module....
Alfredo Ferro, Rosalba Giugno, Giuseppe Pigola, Al...
BMCBI
2008
126views more  BMCBI 2008»
13 years 8 months ago
Methods for evaluating gene expression from Affymetrix microarray datasets
Background: Affymetrix high density oligonucleotide expression arrays are widely used across all fields of biological research for measuring genome-wide gene expression. An import...
Ning Jiang, Lindsey J. Leach, Xiaohua Hu, Elena Po...
BMCBI
2006
116views more  BMCBI 2006»
13 years 8 months ago
Optimized mixed Markov models for motif identification
Background: Identifying functional elements, such as transcriptional factor binding sites, is a fundamental step in reconstructing gene regulatory networks and remains a challengi...
Weichun Huang, David M. Umbach, Uwe Ohler, Leping ...
IPMI
1997
Springer
14 years 8 months ago
Automatical Adaption of the Stereotactical Coordinate System in Brain MRI Datasets
Abstract: Neuroanatomical and neurofunctional studies are often referenced to a high resolution MR brain dataset. To allow intersubject comparisons of cortical structures, one need...
Frithjof Kruggel, Gabriele Lohmann