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BMCBI
2008
101views more  BMCBI 2008»
13 years 9 months ago
Scipio: Using protein sequences to determine the precise exon/intron structures of genes and their orthologs in closely related
Background: For many types of analyses, data about gene structure and locations of non-coding regions of genes are required. Although a vast amount of genomic sequence data is ava...
Oliver Keller, Florian Odronitz, Mario Stanke, Mar...
BMCBI
2008
171views more  BMCBI 2008»
13 years 9 months ago
Fuzzy association rules for biological data analysis: A case study on yeast
Background: Last years' mapping of diverse genomes has generated huge amounts of biological data which are currently dispersed through many databases. Integration of the info...
Francisco J. Lopez, Armando Blanco, Fernando Garci...
BMCBI
2008
144views more  BMCBI 2008»
13 years 9 months ago
PDTD: a web-accessible protein database for drug target identification
Background: Target identification is important for modern drug discovery. With the advances in the development of molecular docking, potential binding proteins may be discovered b...
Zhenting Gao, Honglin Li, Hailei Zhang, Xiaofeng L...
BMCBI
2008
132views more  BMCBI 2008»
13 years 9 months ago
Mixture models for analysis of melting temperature data
Background: In addition to their use in detecting undesired real-time PCR products, melting temperatures are useful for detecting variations in the desired target sequences. Metho...
Christoffer Nellåker, Fredrik Uhrzander, Joa...
BMCBI
2008
137views more  BMCBI 2008»
13 years 9 months ago
Evading the annotation bottleneck: using sequence similarity to search non-sequence gene data
Background: Non-sequence gene data (images, literature, etc.) can be found in many different public databases. Access to these data is mostly by text based methods using gene name...
Michael J. Gilchrist, Mikkel B. Christensen, Richa...